- "Bringing you some all time classics from the Tuff Gong family."
- — GTA IV Website
Tuff Gong Radio is considered a more traditional counterpart to Massive B Soundsystem. Tuff Gong Radio plays traditional reggae, whereas Massive B Soundsystem plays dancehall, which is a commercialised version of reggae.
The station's name and playlist are a tribute to Bob Marley, a prominent reggae artist. Indeed, the station's playlist consists of nothing but music from Bob Marley & The Wailers, as well as Bob Marley's two sons, Stephen Marley and Damian Marley. The station's name and logo comes from the record label founded by Bob Marley & The Wailers in 1970, which their most prominent work was released on. The "Tuff Gong" name itself was a nickname of Bob Marley's, which derived from that of Rastafari leader Leonard "The Gong" Howell.
As RamJam FM replaces Tuff Gong Radio and Massive B Soundsystem in Episodes from Liberty City, the station is not available in the compilation's version of The Lost and Damned and The Ballad of Gay Tony.
- Stephen Marley - "Chase Dem" (2005)
- Bob Marley & The Wailers - "Concrete Jungle" (The Unreleased Original Jamaican Version) (1973)
- Bob Marley & The Wailers - "Pimper's Paradise" (1980)
- Bob Marley & The Wailers - "Rat Race" (1975)
- Bob Marley & The Wailers - "Rebel Music (3 O'Clock Roadblock)" (1978)
- Bob Marley & The Wailers - "Satisfy My Soul" (1978)
- Bob Marley & The Wailers - "So Much Trouble In The World" (1979)
- Bob Marley & The Wailers and Damian Marley - "Stand Up Jamrock" (2005)
- Bob Marley & The Wailers - "Wake Up & Live (Parts 1 & 2)" (1979)
- Bob Marley & The Wailers - "Get Up, Stand Up" (1973)
- In GTA IV's audio files, Tuff Gong Radio is named "Babylon". This is a reference to the Rastafari term referring to the corrupt and decadent Western society.
- Tuff Gong Radio is one of Little Jacob's favourite radio stations, though Michelle does not like this station.
- Tuff Gong Radio is the default station in Roman Bellic's Cavalcade taxis.
- Bob Marley's song "Exodus" is used in the station's jingle.