Carl goes to Smoke's house. Upon arriving there, he finds Officer Frank Tenpenny and Officer Eddie Pulaski leaving. Smoke informs Carl that they are attempting to extract information from him. Smoke tells CJ that his cousin, Mary is coming to the town from Mexico and he's going to pick her up.
The two drive to a place to meet two Vagosgang members. After a short mixed Spanish conversation, Smoke knocks one out using a baseball bat while the other runs away. Carl manages to catch and kill him.
In order to complete the mission the player must:
Get into Big Smoke's car.
Drive Big Smoke to the meet. If you need a weapon, go to Emmet's house.
Chase down the gang member.
You can only use the Super Sprint for a short time before becoming tired.
The more you sprint, the higher your stamina will become, allowing you to exert yourself for longer.
If Carl somehow identifies where the Sentinel spawn point is, it is possible to destroy the car before the Vagos gang member approaches it and then the gangbanger will flee instantly after seeing the wreck. Carl can approach the car by quickly outrunning the target.
If the player decides to chase after the Vagos member in a car after he gets into the Sentinel, the car will not have a scripted route and just drive around. Continuing chasing the car for too long will cause the game to tell the player to kill the target before the car reaches the destination. The car will stop near Carniceria el Pueblo in Las Colinas and a cutscene will play, showing the target getting into the house nearby and the Sentinel driving away. The mission will fail and the game will say Carl has lost the gang member. (Confirmed on PC and mobile versions.)
Big Smoke says his cousin is called "Mary", which is a reference to Mary Jane, slang for marijuana.
This is the only mission given by Big Smoke where Carl is not required to use a motorbike.
However, even though he is required to use a yellow Sanchez in the next mission, he does not need to.
If the Sentinel is destroyed or the driver is killed before he runs to it, he will just flee from the scene with a random NPC scream, giving the player time to kill him.
If the target is killed while in sight of the Sentinel, after the mission is completed, the Sentinel driver will drive the vehicle away rapidly.
The Sentinel is locked if the driver is waiting for the gangbanger in it. If the driver is killed by whatever reason, Carl can enter the vehicle and it can be kept after killing the gangbanger, but it will lock itself if the player simply gets out of the car.
The line the second Vagos member uses roughly translates to, "fuck you, bastard," and afterwards, "fuck your mother, dickhead."
In this mission, it is revealed that Big Smoke knows how to speak (some) Spanish.
Earlier during the game's development, this mission also required Carl to drive Smoke back home. CJ asked Smoke about Tenpenny's visit at the start of the mission, which Smoke replied that he does not know who Tenpenny is. It is speculated that part was cut because it was strongly foreshadowing Smoke's betrayal. The part can be seen in this video.
If the player fails the mission, and has over 50% fat, Carl will receive a phone call from Smoke shortly afterwards, who tells Carl that he was "letting himself go" and needed to visit the Gym, and Carl sarcastically declines his suggestion. This can be seen in this video.
This is the only time the interior of Big Smoke's house is seen (at least part of it). Outside of this cutscene, if managing to go through the building, the interior will be absent, as it is scripted to spawn only in the cutscene.
Officer Frank Tenpenny and Officer Eddie Pulaski leaving Big Smoke's house.