This list contains the missions Michael De Santa appears in.
Mission appearances
Story Missions
- Prologue
- Franklin and Lamar
- Complications
- Father/Son (Boss)
- Marriage Counseling (Boss)
- Friend Request (Boss, Michael Only)
- Daddy's Little Girl (Michael Only)
- Casing the Jewel Store (Michael Only)
- Carbine Rifles (only if "Loud" was chosen)
- Bugstars Equipment (only if "Smart" was chosen)
- BZ Gas Grenades (only if "Smart" was chosen)
- The Jewel Store Job
- Mr. Phillips
- Fame or Shame (Boss)
- Dead Man Walking (Michael Only)
- Three's Company
- By The Book
- Did Somebody Say Yoga? (Boss, Michael Only)
- The Merryweather Heist
- Trash Truck (can be completed as any character)
- Boiler Suits (can be completed as any character)
- Masks (can be completed as any character)
- Tow Truck (can be completed as any character)
- Blitz Play
- I Fought The Law
- Mr. Richards (Michael Only)
- Caida Libre
- Minor Turbulence
- Paleto Score Setup
- Military Hardware (can be completed as any character)
- Predator
- The Paleto Score
- Derailed
- Monkey Business
- Hang Ten
- Surveying the Score
- Bury the Hatchet (Boss)
- Fresh Meat
- The Ballad of Rocco (Michael Only)
- Cleaning Out the Bureau (Michael Only)
- Reuniting the Family (Boss, Michael Only)
- Architect's Plans
- Legal Trouble (Michael Only)
- Fire Truck (only if "Fire Crew" was chosen, can be completed as either Michael or Franklin)
- The Bureau Raid
- The Wrap Up
- Meltdown (Michael Only)
- Planning the Big Score
- Stingers (only if "Subtle" was chosen, can be completed as any character)
- Gauntlet (only if "Subtle" was chosen, can be completed as any character)
- Driller (only if "Obvious" was chosen, can be completed as any character)
- Sidetracked (only if "Obvious" was chosen, can be completed as any character)
- The Big Score
- Something Sensible (only if "Option A" was chosen)
- The Time's Come (only if "Option B" was chosen; killed)
- The Third Way (only if "Option C" was chosen)
Side Missions
Optional Missions
Strangers and Freaks