He, along with Julio, Paulo and Ricardo inform El Burro of some buses being used to smuggle people across the border, with the protagonist destroying the buses in orders from El Burro. The protagonist later takes money to the informants as payment.
Manolito is the second to be paid-off, after Julio, and is encountered in northeast Glen Wood. When he is encountered, he complain about the protagonist's lateness no manner how fast the player reach him. Then, he leave the area driving a red Itali GTO while El Burro mentions how Manolito is always angry, and that he may have to eliminate Manolito someday because of this.