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Events of GTA IV
Spoiler Warning:Plot details, ending details, or both are in the text which follows.
During the mission Blood Brothers, Francis McReary explains to Niko that he wants his brother Derrick dead for "the good of the community", when in reality, Derrick is intending to leak incriminating information about Francis to a reporter, jeopardizing his career in the police force.
Francis is meeting Derrick at a park in Lancet to give Niko the opportunity to kill him. Niko must choose between the two brothers, and for the second time, kill one or the other.