Isaac (disambiguation)

Isaac may refer to;
 * Isaac Roth - a diamond dealer and member of the Jewish Mob in Grand Theft Auto IV
 * Isaac Penny - a businessman and target for Lester's Assassinations in Grand Theft Auto V
 * Isaac (GTA V) - a deceased character featured as a key character in Murder Mystery side mission in the enhanced version of Grand Theft Auto V
 * Isaac Hammerstein - a businessman and Lazlow Jones' uncle mentioned in The Ballad Of Gay Tony
 * Isaac Hammerstein and Daughters Funeral Services - the business owned by the character mentioned above